Oxidative DNA damage is significantly correlated with flow-mediated dilation in patients with coronary artery disease

Yurdakul, Selen; ÖZBEN SADIÇ, BESTE; Bilge, Ahmet; Turkoglu, Umit; Arkaya, Selda; Nisanci, Yilmaz

doi:10.2310/jim.0b013e318180a91f

Oxidative DNA damage is significantly correlated with flow-mediated dilation in patients with coronary artery disease

Yurdakul S., ÖZBEN SADIÇ B., Bilge A. K., Turkoglu U. M., Arkaya S., Nisanci Y.

JOURNAL OF INVESTIGATIVE MEDICINE, cilt.56, sa.7, ss.925-930, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 56 Sayı: 7
Basım Tarihi: 2008
Doi Numarası: 10.2310/jim.0b013e318180a91f
Dergi Adı: JOURNAL OF INVESTIGATIVE MEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.925-930
İstanbul Üniversitesi Adresli: Evet

Özet

Background: Oxidative DNA damage was increased in patients with coronary artery disease (CAD) and correlated with the severity of the disease. Endothelial dysfunction plays a major role in atherosclerotic process. The aim of this study was to explore a relation between oxidative DNA damage and endothelial function in patients with CAD.