Oxidative DNA damage is significantly correlated with flow-mediated dilation in patients with coronary artery disease

Yurdakul, Selen; ÖZBEN SADIÇ, BESTE; Bilge, Ahmet; Turkoglu, Umit; Arkaya, Selda; Nisanci, Yilmaz

doi:10.2310/jim.0b013e318180a91f

Oxidative DNA damage is significantly correlated with flow-mediated dilation in patients with coronary artery disease

Yurdakul S., ÖZBEN SADIÇ B., Bilge A. K., Turkoglu U. M., Arkaya S., Nisanci Y.

JOURNAL OF INVESTIGATIVE MEDICINE, vol.56, no.7, pp.925-930, 2008 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 56 Issue: 7
Publication Date: 2008
Doi Number: 10.2310/jim.0b013e318180a91f
Journal Name: JOURNAL OF INVESTIGATIVE MEDICINE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.925-930
Istanbul University Affiliated: Yes

Abstract

Background: Oxidative DNA damage was increased in patients with coronary artery disease (CAD) and correlated with the severity of the disease. Endothelial dysfunction plays a major role in atherosclerotic process. The aim of this study was to explore a relation between oxidative DNA damage and endothelial function in patients with CAD.