Atıf İçin Kopyala
Yarman S., Serbest E., Selcukbiricik O. S., Tuncer F. N.
TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM, cilt.26, sa.3, ss.109-114, 2022 (ESCI)
-
Yayın Türü:
Makale / Tam Makale
-
Cilt numarası:
26
Sayı:
3
-
Basım Tarihi:
2022
-
Doi Numarası:
10.5152/tjem.2022.22022
-
Dergi Adı:
TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM
-
Derginin Tarandığı İndeksler:
Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, EMBASE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
-
Sayfa Sayıları:
ss.109-114
-
Anahtar Kelimeler:
Ectopic ACTH secretion, lung carcinoids, MEN1 gene, prognosis, NEOPLASIA TYPE-1 MEN1, NEUROENDOCRINE TUMORS, ENDOCRINE, GENE, MUTATIONS, DIAGNOSIS, IDENTIFICATION, MANAGEMENT
-
İstanbul Üniversitesi Adresli:
Evet
Özet
Objective: Lung carcinoids represent a small portion of all lung tumors and about 1%-5% are associated with ectopic adrenocorticotropic hormone secretion, representing 1%-10% of Cushing's syndrome. They occur both sporadically and rarely in association with multiple endocrine neoplasia type 1. MEN1 variations were detected in approximately 16% of sporadic cases with seldom reports about disease prognosis. This study aimed to identify MEN1 variants in our cohort of sporadic lung carcinoids to associate with disease outcome following surgery.