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Yarman S., Serbest E., Selcukbiricik O. S., Tuncer F. N.
TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM, vol.26, no.3, pp.109-114, 2022 (ESCI)
Article / Article
TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM
Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, EMBASE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
Ectopic ACTH secretion, lung carcinoids, MEN1 gene, prognosis, NEOPLASIA TYPE-1 MEN1, NEUROENDOCRINE TUMORS, ENDOCRINE, GENE, MUTATIONS, DIAGNOSIS, IDENTIFICATION, MANAGEMENT
Istanbul University Affiliated:
Objective: Lung carcinoids represent a small portion of all lung tumors and about 1%-5% are associated with ectopic adrenocorticotropic hormone secretion, representing 1%-10% of Cushing's syndrome. They occur both sporadically and rarely in association with multiple endocrine neoplasia type 1. MEN1 variations were detected in approximately 16% of sporadic cases with seldom reports about disease prognosis. This study aimed to identify MEN1 variants in our cohort of sporadic lung carcinoids to associate with disease outcome following surgery.