Infliximab does not suppress the tuberculin skin test (purified protein derivative)

Hatemi, Gülen; Melikoglu, Melike; Fresko, Izzet; Masatlioglu, Seval; Tascilar, Koray; Yazici, Hasan

Infliximab does not suppress the tuberculin skin test (purified protein derivative)

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Hatemi G. , Melikoglu M. , Fresko I., Masatlioglu S., Tascilar K., Yazici H.

JOURNAL OF RHEUMATOLOGY, vol.34, no.3, pp.474-480, 2007 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 34 Issue: 3
Publication Date: 2007
Title of Journal : JOURNAL OF RHEUMATOLOGY
Page Numbers: pp.474-480

Abstract

Objective. Tuberculin skin testing with purified protein derivative (PPD) is part of tuberculosis (TB) screening in patients receiving infliximab. We assessed whether infliximab, a strong inhibitor of inflammation, suppressed dermal induration, the outcome of this test. We also reassessed the booster phenomenon and the interobserver variability in tuberculin testing.