Endometrial malignancies arising on endometrial polyps and precursor lesions

Eken M. K. , Kaygusuz E. I. , Ilhan G., Devranoglu B., Cogendez E., Keyif B., ...Daha Fazla

EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, cilt.37, ss.827-832, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 37 Konu: 6
  • Basım Tarihi: 2016
  • Doi Numarası: 10.12892/ejgo3256.2016
  • Sayfa Sayıları: ss.827-832


Introduction: Polyps are covered with endometrial epithelium and composed of varying proportions of gland, stroma, and blood vessels. Traditionally, endometrial polyps are accepted as a precursor of cancer. The aim of this study was to evaluate the relationship between malignancies arising on endometrial polyps and precursor lesions of these malignancies. Materials and Methods: Data of patients who underwent total abdominal hysterectomy because of a malignancy diagnosed on endometrial polyps were obtained retrospectively from pathology archives. Results: When all malignancies on endometrial polyp were considered, 37% of cases were Type I, 55% were Type II, and 7% were carcinosarcoma. Endometrial intraepithelial carcinoma (EIC) was detected as tumor-adjacent areas on the polyp in eight of the patients who were diagnosed with serous carcinoma. Conclusion: The authors found a precursor lesion in 20 (74%) of their patients who showed endometrial malignancy developing on endometrial polyps. Even when an overt malignancy is not detected on polyps in the curettage material, precursor lesions should be carefully searched.