Effects of selective COX-2 inhibitors on the gastric permeability of sucrose: a controlled study with placebo and ibuprofen

Ekenel, Meltem; AVSAR, Emin; IMERYUZ, N; YUKSEL, M; HAKLAR, G; KOCAKAYA, O; TOZUN, N

doi:10.1097/00042737-200304000-00011

Effects of selective COX-2 inhibitors on the gastric permeability of sucrose: a controlled study with placebo and ibuprofen

Atıf İçin Kopyala

Ekenel M., AVSAR E., IMERYUZ N., YUKSEL M., HAKLAR G., KOCAKAYA O., ...Daha Fazla

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.15, sa.4, ss.403-406, 2003 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 15 Sayı: 4
Basım Tarihi: 2003
Doi Numarası: 10.1097/00042737-200304000-00011
Dergi Adı: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.403-406
İstanbul Üniversitesi Adresli: Hayır

Özet

Objective Acute and chronic use of non-steroidal anti-inflammatory drugs can increase gastrointestinal permeability. Celecoxib, which selectively inhibits the enzyme cyclooxygenase-2, is a novel anti-inflammatory drug with minimal gastrointestinal toxic effects while retaining anti-inflammatory efficacy. Our aim was to assess the potential effects of celecoxib on gastric permeability in comparison with placebo and ibuprofen.