Atıf İçin Kopyala
Kaynak D., Yıldız M., Sahin S., Haslak F., Gunalp A., Adrovic A., ...Daha Fazla
CLINICAL RHEUMATOLOGY, cilt.42, sa.1, ss.245-251, 2023 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
42
Sayı:
1
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Basım Tarihi:
2023
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Doi Numarası:
10.1007/s10067-022-06370-1
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Dergi Adı:
CLINICAL RHEUMATOLOGY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
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Sayfa Sayıları:
ss.245-251
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Anahtar Kelimeler:
NLRP3 gene variants, NLRP3 serum levels, PFAPA syndrome, FAMILIAL MEDITERRANEAN FEVER, RHEUMATOID-ARTHRITIS, AUTOINFLAMMATORY DISEASES, INFLAMMASOME GENES, ACTIVATION, DIAGNOSIS, DISORDER
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İstanbul Üniversitesi Adresli:
Evet
Özet
Objectives Although most of the autoinfammatory disorders have a confirmed genetic cause, periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome still has an unknown genetic background. However, familial cases of PFAPA syndrome have been reported suggesting a genetic its basis. PFAPA syndrome may also be considered an infammasome disorder as variants in infammasome-associated genes such as CARD8, NLRP3, and MEFV have been reported to contribute to the disease.