Liver and pancreas: 'Castor and Pollux' regarding the relationship between hepatic steatosis and pancreas exocrine insufficiency

Boga S., Koksal A. R., Sen I., Yeniay M. K., Ozguven M. B. Y., Serin E., ...More

PANCREATOLOGY, vol.20, no.5, pp.880-886, 2020 (SCI-Expanded)

  • Publication Type: Article / Article
  • Volume: 20 Issue: 5
  • Publication Date: 2020
  • Doi Number: 10.1016/j.pan.2020.04.020
  • Journal Name: PANCREATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.880-886
  • Keywords: Fat, Elastase, nafld, FECAL ELASTASE-1 CONCENTRATIONS, SCANNING-ELECTRON-MICROSCOPY, BETA-CELL FUNCTION, DIABETES-MELLITUS, FATTY PANCREAS, QUANTIFICATION, ASSOCIATION, PREVALENCE, HISTOLOGY, FIBROSIS
  • Istanbul University Affiliated: Yes

Abstract

Background: Pancreatic exocrine insufficiency (PEI) is found in 30-50% of diabetes mellitus (DM). Insulin resistance is triggering factor in both DM and nonalcoholic fatty liver disease (NAFLD). Therefore, we aimed to investigate frequency of PEI in NAFLD, and relationship of fecal pancreatic elastase (PE) levels with liver histology and pancreatic fat.