Nerve Growth Factor Neutralization Suppresses beta-Cell Proliferation Through Activin A and Betacellulin

Gezginci-Oktayoglu S., Karatug A., Bolkent S.

PANCREAS, cilt.44, sa.2, ss.243-249, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1097/mpa.0000000000000243
  • Dergi Adı: PANCREAS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.243-249
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective: The aim of this study was to investigate the effects of nerve growth factor (NGF) neutralization on synthesis and secretion of activin A (Act-A) and betacellulin (BTC) from primary beta cells and the importance of these relations for beta-cell proliferation.