Anti-angiogenic effect of a Palladium(II)-Saccharinate Complex of Terpyridine in vitro and in vivo

Ikitimur-Armutak, Elif; Gurel-Gurevin, Ebru; KIYAN, HÜLYA; Aydinlik, Seyma; YILMAZ, VEYSEL; Dimas, Konstantinos; ULUKAYA, Engin

doi:10.1016/j.mvr.2016.09.002

Anti-angiogenic effect of a Palladium(II)-Saccharinate Complex of Terpyridine in vitro and in vivo

Ikitimur-Armutak E. I., Gurel-Gurevin E., KIYAN H. T., Aydinlik S., YILMAZ V. T., Dimas K., ...Daha Fazla

MICROVASCULAR RESEARCH, cilt.109, ss.26-33, 2017 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 109
Basım Tarihi: 2017
Doi Numarası: 10.1016/j.mvr.2016.09.002
Dergi Adı: MICROVASCULAR RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.26-33
İstanbul Üniversitesi Adresli: Evet

Özet

Anti-angiogenic activity of palladium (Pd) (II)-based complexes is unknown despite their quite powerful anticancer activity. This study was therefore carried out to evaluate both in vivo anti-angiogenic effect and in vitro cytotoxic activity of a Pd(II)-based complex. ([Pd(sac)(terpy)](sac).4H(2)O(sac = saccharinate and terpy = 2,2':6',2 ''-terpyridine)) on HUVEC cells.