Research Information System
Other, pp.235, 2017
10.5505/2017ichc.PP-70 [Structure and function of the cell] Effects of constant magnetic field of platelet function Cigdem Bayram Gürel1 , Gülsel Ayaz1 , Handan Tuncel2 , Tunaya Kalkan2 , Nazmiye Kurşun3 , Turgut Ulutin1 1 Department of Medical Biology, Medical Faculty of Cerrahpaşa, University of İstanbul, İstanbul, Turkey 2 Department of Biophysic, Medical Faculty of Cerrahpaşa, University of İstanbul, İstanbul, Turkey 3 Department of Biostatistic, Medical Faculty of Ankara, University of Ankara, Ankara, Turkey Platelets secrete substances required for coagulation and inflammation, as well as membrane proteins are 4-7 microns in diameter through blood cells which are important tools. Although many studies have investigated the effects of today’s magnetic field life cycle on the blood cells its mechanism of action is still unclear. Some studies suggest that especially low constant magnetic field activates leukocytes, increases their number, yet its effect on thrombocytes are not well established. We forsee that constant magnetic field may effect the functions of thrombocytes and enable there to survive longer outside of the body. For this reason we expose the thrombocytes to magnetic field with different power(2mT,5mT,40mT) in different time periods (5’,15’,30’). The measurements of thrombocyte aggregation were performed via agregometer in different time stops(0,24,40,48). ADP stimulates platelet aggregation. The 24h aggregation of the thrombocytes in response to 5mT 15 min. and 30 min. incubation was higher than that of the initial aggregation (slope p=0.008, Amplitude p=0.026). There were no difference between 15min. and 30min. The 48h measurement of 2 mT 15 min. and 30min. threated cells were higher than their initial measurements(p=0.038). With aggregation performed in 2mT is higher than the aggregation performed in 5mT(p=0,032). Platelet function responds to a magnetic field, and this response is a result worth further exploration. Keywords: platelet function, constant magnetic field, agregation