The effects of sunitinib malate used in targeted therapy on the proliferation of HeLa cells in vitro

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Tekisogullari K., Topcul M. R.

JOURNAL OF BUON, vol.18, no.1, pp.253-260, 2013 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 18 Issue: 1
• Publication Date: 2013
• Journal Name: JOURNAL OF BUON
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.253-260
• Keywords: apoptotic index, cancer, mitotic index, sunitinib, sutent, targeted cancer therapy, TYROSINE KINASE INHIBITOR, TELOMERE DYSFUNCTION, SU11248, ANGIOGENESIS, MECHANISMS, GROWTH, FUSION
• Istanbul University Affiliated: Yes

Abstract

Purpose: In this study, the antiproliferative and apoptotic effects of sunitinib (SU-11248, Sutent) which is used for targeted therapy was evaluated on HeLa cell line originated from human cervix carcinoma.