JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, cilt.68, sa.1, ss.19-21, 2005 (ESCI)
The iron in the hemoglobin molecule is in ferrous state (Fe++). The oxidation of iron from ferrous to ferric (Fe+++) state causes methemoglobinemia. This reaction decreases the oxygen-carrying capacity of hemoglobin leading to hypoxemia of the peripheral tissues and even to death in severe cases. Methemoglobinemia is frequently related to chemical substances. However, hereditary or idiopathic cases have also been described. Methemoglobinemia due to local anesthetic drugs may occur especially in newborn infants. Here, we presented an adult case in which methemoglobinemia developed after the administration of prilocaine prior to an epilation procedure.