Assessment of macroprolactinemia inpatients with prolactinoma

Dogansen S. C., Yalin G., Yarman S.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.43, sa.1, ss.71-75, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1515/tjb-2017-0062
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.71-75
  • Anahtar Kelimeler: Prolactinoma, Macroprolactinemia, Tumoral hyperprolactinemia, Big big prolactin, PEG precipitation method, POLYETHYLENE-GLYCOL PRECIPITATION, CLINICAL-PRACTICE, PITUITARY-TUMOR, BIG PROLACTIN, HYPERPROLACTINEMIA, SERUM, PRL, AUTOANTIBODIES, DIAGNOSIS, SOCIETY
  • İstanbul Üniversitesi Adresli: Evet

Özet

Purpose: Macroprolactin, the high-molecular mass prolactin isoform, is considered to be an inactive product with extrapituitary origin. Although macroprolactinemia is considered a benign condition, there is evidence of overlapping clinical features among patients with hyperprolactinemia. Data on the prevalence of macroprolactinemia in prolactinomas is also quite limited. The aim of this study was to assess the prevalence of macroprolactinemia in our patients with prolactinoma.