Assessment of macroprolactinemia inpatients with prolactinoma

Dogansen S. C., Yalin G., Yarman S.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.43, no.1, pp.71-75, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.1515/tjb-2017-0062
  • Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.71-75
  • Keywords: Prolactinoma, Macroprolactinemia, Tumoral hyperprolactinemia, Big big prolactin, PEG precipitation method, POLYETHYLENE-GLYCOL PRECIPITATION, CLINICAL-PRACTICE, PITUITARY-TUMOR, BIG PROLACTIN, HYPERPROLACTINEMIA, SERUM, PRL, AUTOANTIBODIES, DIAGNOSIS, SOCIETY
  • Istanbul University Affiliated: Yes

Abstract

Purpose: Macroprolactin, the high-molecular mass prolactin isoform, is considered to be an inactive product with extrapituitary origin. Although macroprolactinemia is considered a benign condition, there is evidence of overlapping clinical features among patients with hyperprolactinemia. Data on the prevalence of macroprolactinemia in prolactinomas is also quite limited. The aim of this study was to assess the prevalence of macroprolactinemia in our patients with prolactinoma.