Evaluation of the clinical utility of urocortin 1 in systolic heart failure

Yildirim E., Keles I., Cakmak H. A., Cosansu K., Can G., Ikitimur B.

KARDIOLOGIA POLSKA, vol.72, no.5, pp.452-458, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 72 Issue: 5
  • Publication Date: 2014
  • Doi Number: 10.5603/kp.a2013.0353
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.452-458
  • Istanbul University Affiliated: Yes


Background: Urocortin 1 (UCN1) has cardiostimulatory, vasodilatory, diuretic and natriuretic effects, and its expression increases in heart failure (HF). Aim: To determine UCN1 levels in patients with HF, to evaluate UCN1's relationship with various clinical parameters, and to assess UCN1 as a diagnostic marker in HF, compared to pro-B-type natriuretic peptide (pro-BNP).