Atıf İçin Kopyala
Yılmaz H., Unlucerci Y. M. Y., Gurdol F. M., İşbilen E., İsbir T.
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY, cilt.44, sa.5, ss.423-427, 2004 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
44
Sayı:
5
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Basım Tarihi:
2004
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Doi Numarası:
10.1111/j.1479-828x.2004.00283.x
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Dergi Adı:
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.423-427
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Anahtar Kelimeler:
hyperhomocysteinaemia, methylene tetrahydrofolate reductase gene, pre-eclampsia, Turkish, SERUM HOMOCYST(E)INE LEVELS, FACTOR-V-LEIDEN, VASCULAR-DISEASE, COMMON MUTATION, RISK-FACTOR, CARDIOVASCULAR-DISEASE, HOMOCYSTEINE, PREGNANCY, WOMEN, SUSCEPTIBILITY
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İstanbul Üniversitesi Adresli:
Evet
Özet
Background: Hyperhomocysteinaemia is a common finding in a wide variety of pathological conditions that exhibit endothelial disturbances. In the pathogenesis of pre-eclampsia, endothelial cell activation or dysfunction has been proposed as a central feature, and the presence of hyperhomocysteinaemia in varying degrees has been detected. One of the known causes of hyperhomocysteinaemia is polymorphism in the methylenetetrahydrofolate reductase gene that lowers the activity of the enzyme.