Selenium supplementation ameliorates electromagnetic field-induced oxidative stress in the HEK293 cells

Ozsobaci, Nural; Ergun, Dilek; Durmus, Sinem; Tuncdemir, Matem; Uzun, Hafize; Gelisgen, Remise; Ozcelik, Derviş

doi:10.1016/j.jtemb.2018.04.008

Selenium supplementation ameliorates electromagnetic field-induced oxidative stress in the HEK293 cells

Atıf İçin Kopyala

Ozsobaci N. P., Ergun D. D., Durmus S., Tuncdemir M., Uzun H., Gelisgen R., ...Daha Fazla

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, cilt.50, ss.572-579, 2018 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 50
Basım Tarihi: 2018
Doi Numarası: 10.1016/j.jtemb.2018.04.008
Dergi Adı: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.572-579
İstanbul Üniversitesi Adresli: Evet

Özet

There is a widespread use of 2.4 GHz electromagnetic radiation emitting devices especially in communication and education. Recent studies show the adverse effects of electromagnetic fields (EMF) such as oxidative stress, cellular damage and apoptosis on tissues. Selenium (Se) has an antioxidant properties by inhibiting oxidative damage being within the structure of antioxidant enzymes like glutathione peroxidase (GSH-Px) and it has also regulatory function for cell cycle and apoptosis. The aim of this study was to investigate the effect of Se on 2.4 GHz frequency EMF exposed human embryonic kidney cells (HEK293) by means of alterations in apoptotic and oxidative stress parameters.