Intraportal Transplantation of Pancreatic Islets in Mouse Model
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, no.135, 2018 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: Issue: 135
- Publication Date: 2018
- Doi Number: 10.3791/57559
- Journal Name: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Istanbul University Affiliated: Yes
Abstract
Pancreatic islet transplantation to reduce hyperglycemia is highly successful in rodents with chemically-induced diabetes. The most common transplantation site in experimental islet transplantation is the kidney capsule. However, as less is known about the interaction of pancreatic islets with blood constituents, it also makes sense to utilize the portal vein approach in experimental islet transplantation.