Assessment of platelet aspirin responsiveness in Turkish Population with PFA-100, serum thromboxane B-2, soluble CD40 ligand and soluble P-Selectin]

Saka B., Genc S., Eroglu H., Akpinar T. S., Karadag A., Kilic L., ...Daha Fazla

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.38, sa.1, ss.63-67, 2013 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5505/tjb.2013.75437
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.63-67
  • Anahtar Kelimeler: Aspirin resistance, PFA-100, thromboxane B-2, (TXB2), CD40 ligand, sP-selectin, FUNCTION ANALYZER PFA-100, LOW-DOSE ASPIRIN, CARDIOVASCULAR-DISEASE, HEALTHY-VOLUNTEERS, DIABETES-MELLITUS, RESISTANCE, BIOSYNTHESIS, AGGREGATION, VARIABILITY, OMEPRAZOLE
  • İstanbul Üniversitesi Adresli: Evet

Özet

Aim: Recurrent thromboembolic vascular events have been reported in 5.5 to 60% of the population despite aspirin therapy. We aimed to determine the frequency of aspirin non-responsiveness in our population with "Platelet Function Analyzer-100 Closure Time" (PFA-100 CT) and serum tromboxane B-2, soluble CD40 Ligand and soluble P-selectin levels.