Evidence for an association between tumor necrosis factor-alpha levels and lithium response


Guloksuz S., ALTINBAS K., Cetin E. A. , Kenis G., Gazioglu S. B. , Deniz G. , ...Daha Fazla

JOURNAL OF AFFECTIVE DISORDERS, cilt.143, ss.148-152, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 143
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.jad.2012.04.044
  • Dergi Adı: JOURNAL OF AFFECTIVE DISORDERS
  • Sayfa Sayıları: ss.148-152

Özet

Background: The role of inflammation in bipolar disorder has recently emerged as a potential pathophysiological mechanism. Tumor necrosis factor-alpha (TNIF-alpha) modulation may represent a pathogenic molecular target and a biomarker for staging bipolar disorder. In this context, the possible association between lithium response and TNF-alpha level was examined.