Characteristics Predicting Tuberculosis Risk under Tumor Necrosis Factor-alpha Inhibitors: Report from a Large Multicenter Cohort with High Background Prevalence

Kisacik, Bunyamin; Pamuk, Omer; Onat, Ahmet; Erer, Sait; Hatemi, Gülen; Ozguler, Yesim; Pehlivan, Yavuz; KILIÇ, LEVENT; Ertenli, Ihsan; Can, Meryem; Direskeneli, Haner; Keser, Gokhan; Oksel, Fahrettin; Dalkilic, Ediz; YILMAZ, Sedat; PAY, Salih; Balkarli, Ayse; Cobankara, Veli; Cetin, Gode; Sayarlioglu, Mehmet; Cefle, Ayse; Yazici, Ayten; AVCI, Ali; Terzioglu, Ender; Ozbek, Suleyman; Akar, Servet; Gul, Ahmet

doi:10.3899/jrheum.150177

Characteristics Predicting Tuberculosis Risk under Tumor Necrosis Factor-alpha Inhibitors: Report from a Large Multicenter Cohort with High Background Prevalence

Atıf İçin Kopyala

Kisacik B., Pamuk O. N., Onat A. M., Erer S. B., Hatemi G., Ozguler Y., ...Daha Fazla

JOURNAL OF RHEUMATOLOGY, cilt.43, sa.3, ss.524-529, 2016 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 43 Sayı: 3
Basım Tarihi: 2016
Doi Numarası: 10.3899/jrheum.150177
Dergi Adı: JOURNAL OF RHEUMATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.524-529
Anahtar Kelimeler: TUMOR NECROSIS FACTOR-A INHIBITORS, TUBERCULOSIS REACTIVATION, ISONIAZID, RHEUMATOID-ARTHRITIS, FACTOR ANTAGONISTS, THERAPY, TNF, MORTALITY, INFECTIONS, TERM
İstanbul Üniversitesi Adresli: Evet

Özet

Objective. Screening strategies for latent tuberculosis (TB) before starting tumor necrosis factor (TNF)-alpha inhibitors have decreased the prevalence of TB among patients who are treated with these agents. However, despite vigilant screening, TB continues to be an important problem, especially in parts of the world with a high background TB prevalence. The aim of this study was to determine the factors related to TB among a large multicenter cohort of patients who were treated with anti-TNF.