Decrease in mitochondrial oxidative protein damage parameters in the streptozotocin-diabetic rat

Kayali R., Cakatay U., Telci A., Akcay T., Sivas A., Altug T.

DIABETES-METABOLISM RESEARCH AND REVIEWS, vol.20, no.4, pp.315-321, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 4
  • Publication Date: 2004
  • Doi Number: 10.1002/dmrr.456
  • Journal Name: DIABETES-METABOLISM RESEARCH AND REVIEWS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.315-321
  • Istanbul University Affiliated: Yes

Abstract

Background Many authors have shown that hyperglycemia leads to an increase in oxidative protein damage in diabetes. The aim of this study was to reveal the susceptibility of mitochondria from liver, pancreas, kidney, and skeletal muscle of diabetic Sprague-Dawley rats, a model of type 1 diabetes, to oxidative protein damage.