Relation of aging with oxidative protein damage parameters in the rat skeletal muscle


Cakatay U., Telci A., Kayali R., Tekeli F., Akcay T., Sivas A.

CLINICAL BIOCHEMISTRY, cilt.36, sa.1, ss.51-55, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 1
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1016/s0009-9120(02)00407-1
  • Dergi Adı: CLINICAL BIOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.51-55
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objectives: An increase in oxidative stress may contribute to the development of oxidative protein damage in the aging rat skeletal muscle. Our aim was to reveal protein carbonyl (PCO), advanced oxidation protein products (AOPP), a novel marker of oxidative stress, and protein thiol (P-SH) levels as markers of protein oxidation, as well as lipid hydroperoxide (LHP) levels as a marker of lipid peroxidation, and relation of nitrotyrosine (NT) levels with these markers in skeletal muscle tissue of young, adult, and old male Wistar rats.