Selective molecular biomarkers to predict biologic behavior in pituitary tumors


Sav A., Rotondo F., Syro L. V. , Altinoz M. A. , Kovacs K.

EXPERT REVIEW OF ENDOCRINOLOGY & METABOLISM, cilt.12, ss.177-185, 2017 (ESCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 12 Konu: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1080/17446651.2017.1312341
  • Dergi Adı: EXPERT REVIEW OF ENDOCRINOLOGY & METABOLISM
  • Sayfa Sayıları: ss.177-185

Özet

Introduction: To date, several cell proliferation markers, apoptosis, vascular markers, oncogenes, tumor suppressor genes, cell cycle mediators, microRNA (miRNAs), and long noncoding RNAs (IncRNAs) have been identified to be involved in the tumorigenesis, migration, proliferation and invasiveness of pituitary adenomas. There are still no reliable morphologic markers predictive of pituitary adenoma recurrence. Recent scientific research introduced new techniques to enable us to attain new information on the genesis and biologic behavior of pituitary adenomas.