Anxiety disorders and salivary cortisol levels in older adults: a population-based study

Hek K., Direk N., Newson R. S., Hofman A., Hoogendijk W. J. G., Mulder C. L., ...More

PSYCHONEUROENDOCRINOLOGY, vol.38, no.2, pp.300-305, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.1016/j.psyneuen.2012.06.006
  • Journal Name: PSYCHONEUROENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.300-305
  • Keywords: Cortisol, Anxiety disorder, Older adults, HPA axis, Awakening response, ELDERLY PERSONS, DEPRESSION, RESPONSES, HORMONE, STRESS, TIME
  • Istanbul University Affiliated: No

Abstract

Context: The hypothalamic-pituitary-adrenal (HPA) axis is one of the body's main systems that controls response to stress. It acts through the hormone cortisol. While the dysregulation of cortisol has been associated with anxiety disorders, the evidence is inconsistent. Moreover, only a few small studies have assessed this relationship in older adults.