Corticosteroid treatment normalizes QTc prolongation and improves heart block in an elderly patient with anti-Ro-positive systemic lupus erythematosus

Saribayev M., Tufan F., Oz F., Erer B., Ozpolat T., Ozturk G., ...Daha Fazla

AGING CLINICAL AND EXPERIMENTAL RESEARCH, cilt.26, sa.3, ss.337-339, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 3
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s40520-013-0168-9
  • Dergi Adı: AGING CLINICAL AND EXPERIMENTAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.337-339
  • Anahtar Kelimeler: Systemic lupus erythematosus, Anti-Ro antibody, Heart block, Nephrotic syndrome, ATRIOVENTRICULAR-BLOCK, ANTIBODIES, INTERVAL, ADULTS
  • İstanbul Üniversitesi Adresli: Evet

Özet

Systemic lupus erythematosus (SLE) is a multisystemic disease which potentially involves various organs including the skin, joints, kidneys, liver, hematopoetic system, and serous membranes. It is rarely seen in elderly males. The most common cardiovascular involvement type is pericarditis. Anti-Ro antibodies may be associated with neonatal lupus which causes heart blocks. Recent literature indicates that anti-Ro antibodies may be associated with various rhythm and conduction disturbances in the adulthood. The most common finding associated with anti-Ro antibodies is prolonged corrected QT (QTc) interval. Herein, we present an elderly male patient with anti-Ro-positive SLE associated with prolonged QTc interval and AV blocks that significantly improved after corticosteroid treatment.