An Investigation of <i>SDF1/CXCR4</i> Gene Polymorphisms in Autism Spectrum Disorder: A Family-Based Study.


KARA T., AKALTUN I. , Cakmakoglu B. , Kaya İ. , ZOROGLU S.

Psychiatry investigation, vol.15, no.3, pp.300-305, 2018 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.30773/pi.2017.05.31.2
  • Journal Name: Psychiatry investigation
  • Journal Indexes: Science Citation Index Expanded, Social Sciences Citation Index, Scopus
  • Page Numbers: pp.300-305

Abstract

Objective Autism spectrum disorders (ASD) have a complex pathophysiology including genetic, inflammatory and neurodevelopmental components. We aim to investigate the relationship between ASD and gene polymorphisms of stromal cell-derived factor-1 (SDF-1) and its receptor CXC chemokine receptor-4 (CXCR4), which may affect inflammatory and neurodevelopmental processes.