An Investigation of <i>SDF1/CXCR4</i> Gene Polymorphisms in Autism Spectrum Disorder: A Family-Based Study.

KARA T., AKALTUN I., Cakmakoglu B., Kaya İ., ZOROGLU S.

Psychiatry investigation, cilt.15, sa.3, ss.300-305, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.30773/pi.2017.05.31.2
  • Dergi Adı: Psychiatry investigation
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.300-305
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective Autism spectrum disorders (ASD) have a complex pathophysiology including genetic, inflammatory and neurodevelopmental components. We aim to investigate the relationship between ASD and gene polymorphisms of stromal cell-derived factor-1 (SDF-1) and its receptor CXC chemokine receptor-4 (CXCR4), which may affect inflammatory and neurodevelopmental processes.