An Investigation of SDF1/CXCR4 Gene Polymorphisms in Autism Spectrum Disorder: A Family-Based Study


KARA T., AKALTUN I. , Cakmakoglu B. , Kaya I., ZOROGLU S.

PSYCHIATRY INVESTIGATION, cilt.15, ss.300-305, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 15 Konu: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.30773/pi.2017.05.31.2
  • Dergi Adı: PSYCHIATRY INVESTIGATION
  • Sayfa Sayıları: ss.300-305

Özet

Objective Autism spectrum disorders (ASD) have a complex pathophysiology including genetic, inflammatory and neurodevelopmental components. We aim to investigate the relationship between ASD and gene polymorphisms of stromal cell-derived factor-1 (SDF-1) and its receptor CXC chemokine receptor-4 (CXCR4), which may affect inflammatory and neurodevelopmental processes.