DNA Oxidation and Antioxidant Status in Breast Cancer

Himmetoglu S., Dincer Y., Ersoy Y. E., Bayraktar B., Celik V., Akcay T.

JOURNAL OF INVESTIGATIVE MEDICINE, cilt.57, sa.6, ss.720-723, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Sayı: 6
  • Basım Tarihi: 2009
  • Doi Numarası: 10.2310/jim.0b013e3181adfb5b
  • Dergi Adı: JOURNAL OF INVESTIGATIVE MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.720-723
  • İstanbul Üniversitesi Adresli: Evet

Özet

Purpose; Oxidant/antioxidant balance has been suggested as an important factor for initiation and progression of cancer. The objective of this Study was to determine 8-hydroxydeoxyguanosine (8-OHdG) level as a market of oxidative DNA damage, glutathione peroxidase (G-Px), and superoxide dismutase (SOD) activities as antioxidant activity, in sera from vomen with breast cancer.