Chemokine receptors in advanced breast cancer: differential expression in metastatic disease sites with diagnostic and therapeutic implications

CABIOĞLU, NESLİHAN; Sahin, A.; Morandi, P.; Meric-Bernstam, F.; Islam, R.; Lin, H.; Bucana, C.; Gonzalez-Angulo, A.; Hortobagyi, G.; Cristofanilli, M.

doi:10.1093/annonc/mdn740

Chemokine receptors in advanced breast cancer: differential expression in metastatic disease sites with diagnostic and therapeutic implications

CABIOĞLU N., Sahin A. A., Morandi P., Meric-Bernstam F., Islam R., Lin H. Y., ...Daha Fazla

ANNALS OF ONCOLOGY, cilt.20, sa.6, ss.1013-1019, 2009 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 20 Sayı: 6
Basım Tarihi: 2009
Doi Numarası: 10.1093/annonc/mdn740
Dergi Adı: ANNALS OF ONCOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1013-1019
Anahtar Kelimeler: bone metastases, CCR7, CXCR4, HER2-neu, metastatic breast cancer, LYMPH-NODE METASTASIS, CELL-DERIVED FACTOR-1-ALPHA, CXCR4 EXPRESSION, GROWTH-FACTOR, HER-2 STATUS, BONE, TUMOR, AXIS, CCR7, OVEREXPRESSION
İstanbul Üniversitesi Adresli: Hayır

Özet

Background: We investigated the expression of CXCR4, CCR7, estrogen receptor (ER), progesterone receptor (PR) and HER2-neu in human metastatic breast cancers to determine whether these biological biomarkers were preferentially expressed in any organ-specific metastases.