Design, conduct, and analyses of Breast International Group (BIG) 1-98: A randomized, double-blind, phase-III study comparing letrozole and tamoxifen as adjuvant endocrine therapy for postmenopausal women with receptor-positive, early breast cancer

Giobbie-Hurder A., Price K. N., Gelber R. D.

CLINICAL TRIALS, vol.6, no.3, pp.272-287, 2009 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 3
  • Publication Date: 2009
  • Doi Number: 10.1177/1740774509105380
  • Journal Name: CLINICAL TRIALS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.272-287
  • Istanbul University Affiliated: No


Background Aromatase inhibitors provide superior disease control when compared with tamoxifen as adjuvant therapy for postmenopausal women with endocrine-responsive early breast cancer.