Alteration in Humoral Immunity Is Common Among Family Members of Patients With Common Variable Immunodeficiency

Karakoc-Aydiner E., ÖZEN A. O., Bans S., ERCAN H., Ozdemir C., Barlan I. B.

JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY, vol.24, no.5, pp.346-351, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 5
  • Publication Date: 2014
  • Journal Name: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.346-351
  • Keywords: Allergy, Common variable immunodeficiency (CVID), Consanguinity, Family screening, Immunoglobulin A (IgA) deficiency, Hypogammaglobulinemia, SELECTIVE IGA DEFICIENCY, SUSCEPTIBILITY LOCUS, GENETIC-LINKAGE, CHILDREN, ASTHMA, ATOPY, ASSOCIATION, HAPLOTYPES, MUTATIONS, INFANTS
  • Istanbul University Affiliated: No

Abstract

Background:The prevalence of primary immunodeficiency (PID) in the relatives of patients with common variable immunodeficiency (CVID) and IgA deficiency is high. Allergic disorders have been recorded in patients with humoral immunodeficiency. We aimed to determine the frequency of humoral immunodeficiency and atopy in the relatives of patients with CVID.