Apoptosis in The Development and Pathophysiology of The Limbic System


UYANIKGİL Y., Sumer N. C., Balcioglu H. A.

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, cilt.29, sa.2, ss.431-436, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 29 Sayı: 2
  • Basım Tarihi: 2012
  • Dergi Adı: JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.431-436
  • İstanbul Üniversitesi Adresli: Hayır

Özet

Limbic system is involved in the intangible functions of brain like emotions, inborn and acquired emotional responses, self-awareness, ability to understand intentions of others and and memory. Apoptosis has a critical role in the developing brain and disruption of developmental apoptosis may lead to neurodevelopmental disorders. This review summarizes apoptotic processes in the limbic system during fetal brain development in normal and pathological conditions and focuses on the molecular mechanisms of apoptosis.

 

Limbic system is involved in the intangible functions of brain like emotions, inborn and
acquired emotional responses, self-awareness, ability to understand intentions of others and
and memory. Apoptosis has a critical role in the developing brain and disruption of
developmental apoptosis may lead to neurodevelopmental disorders. This review summarizes
apoptotic processes in the limbic system during fetal brain development in normal and
pathological conditions and focuses on the molecular mechanisms of apoptosis.