Heme Oxygenase-1 Prevents Hyperthyroidism Induced Hepatic Damage via an Antioxidant and Antiapoptotic Pathway

Giris M. , Erbil Y., Depboylu B., Mete O., Turkoglu U., Abbasoglu S. D. , ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.164, ss.266-275, 2010 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 164 Konu: 2
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1016/j.jss.2009.04.013
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Sayfa Sayıları: ss.266-275

Özet

Background The exact pathogenesis of hepatic dysfunction in hyperthyroidism is still unknown We aimed to investigate the pathogenesis of liver dysfunction caused by hyperthyroidism through inducing heme oxygenase-1 (HO-1) expression, which has antioxidant and anti-apoptotic properties