The role of atopy in the pathogenesis of bleomycin pulmonary toxicity.

Ozyigit L. P., Aktas E., Senbas Z. A., Ozturk A. B., Ozturk E., Ergonul M. O., ...Daha Fazla

Respiratory medicine, cilt.155, ss.1-5, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 155
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.rmed.2019.06.020
  • Dergi Adı: Respiratory medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1-5
  • Anahtar Kelimeler: Atopy, Bleomycin, Pulmonary toxicity, Bleomycin hydrolase, Amphiregulin, LUNG FIBROSIS, AMPHIREGULIN, EXPRESSION, RESPONSES, THERAPY, DISEASE, INJURY, TESTS
  • İstanbul Üniversitesi Adresli: Evet

Özet

Introduction: Bleomycin pulmonary toxicity (BPT) is a potentially life-threatening consequence of bleomycin usage in patients. An overproduction of epithelium-derived cytokines, habitually linked to allergic inflammation, has been recently revealed in experimental models of BPT.