A Rapid Method for the Determination of Buprenorphine and Norbuprenorphine in Urine by UPLC-MS/MS

Kul A., Ozdemir M., Ozilhan S., Sağırlı A. O.

CURRENT PHARMACEUTICAL ANALYSIS, cilt.17, sa.7, ss.926-931, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 7
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2174/1573412916999200627010536
  • Dergi Adı: CURRENT PHARMACEUTICAL ANALYSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE
  • Sayfa Sayıları: ss.926-931
  • Anahtar Kelimeler: Buprenorphine, norbuprenorphine, proficiency testing, method validation, UPLC-MS, MS, urine samples, MASS-SPECTROMETRY, UNITED-STATES, ABUSE, DRUGS, BLOOD, METABOLITES, PLASMA
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Buprenorphine is quite common in the illicit market. Buprenorphine-containing drug abuse is frequently encountered in patients. The analysis methods used to determine the abuse of buprenorphine and norbuprenorphine are important for forensic science. Buprenorphine is metabolized to norbuprenorphine by the liver.