The in-vivo assessment of Turkish propolis and its nano form on testicular damage induced by cisplatin

SEVEN P. T., SEVEN İ., KARAKUŞ S., Mutlu S. I., KAYA Ş. Ö., Arkali G., ...More

JOURNAL OF INTEGRATIVE MEDICINE-JIM, vol.19, no.5, pp.451-459, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 5
  • Publication Date: 2021
  • Doi Number: 10.1016/j.joim.2021.08.002
  • Journal Name: JOURNAL OF INTEGRATIVE MEDICINE-JIM
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.451-459
  • Keywords: Cisplatin, Nano-propolis, Reproductive system, Testicular damage, REPRODUCTIVE TOXICITY, PROTECTIVE ROLE, ANTIOXIDANT CAPACITY, OXIDATIVE DAMAGE, SPERM QUALITY, CYCLOSPORINE, EXTRACT, SPERMATOGENESIS, NANOPARTICLES, CHLORPYRIFOS
  • Istanbul University Affiliated: Yes

Abstract

Objective: Chemotherapeutic drugs, such as cisplatin (CP), which are associated with oxidative stress and apoptosis, may adversely affect the reproductive system. This study tests whether administration of propolis and nano-propolis (NP) can alleviate oxidative stress and apoptosis in rats with testicular damage induced by CP.