The in-vivo assessment of Turkish propolis and its nano form on testicular damage induced by cisplatin

SEVEN P. T., SEVEN İ., KARAKUŞ S., Mutlu S. I., KAYA Ş. Ö., Arkali G., ...Daha Fazla

JOURNAL OF INTEGRATIVE MEDICINE-JIM, cilt.19, sa.5, ss.451-459, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 5
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.joim.2021.08.002
  • Dergi Adı: JOURNAL OF INTEGRATIVE MEDICINE-JIM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.451-459
  • Anahtar Kelimeler: Cisplatin, Nano-propolis, Reproductive system, Testicular damage, REPRODUCTIVE TOXICITY, PROTECTIVE ROLE, ANTIOXIDANT CAPACITY, OXIDATIVE DAMAGE, SPERM QUALITY, CYCLOSPORINE, EXTRACT, SPERMATOGENESIS, NANOPARTICLES, CHLORPYRIFOS
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective: Chemotherapeutic drugs, such as cisplatin (CP), which are associated with oxidative stress and apoptosis, may adversely affect the reproductive system. This study tests whether administration of propolis and nano-propolis (NP) can alleviate oxidative stress and apoptosis in rats with testicular damage induced by CP.