Role of estrogen related receptor beta (ESRRB) in DFN35B hearing impairment and dental decay

WEBER M. L., HSIN H., KALAY E., BROZKOVA D. S., SHIMIZU T., Bayram M., ...Daha Fazla

BMC MEDICAL GENETICS, cilt.15, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1186/1471-2350-15-81
  • Dergi Adı: BMC MEDICAL GENETICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Dental caries, Deafness, Dental development, Ear development, Linkage disequilibrium, Genetics, Polymorphisms, GENOME-WIDE ASSOCIATION, HIGH CARIES EXPERIENCE, SCAN, GENE, PREVALENCE, EXPRESSION, MUTATIONS, TYPE-1, DFNB35, ADULTS
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Congenital forms of hearing impairment can be caused by mutations in the estrogen related receptor beta (ESRRB) gene. Our initial linkage studies suggested the ESRRB locus is linked to high caries experience in humans.