Effects of flurbiprofen and tiaprofenic acid on oxidative stress markers in osteoarthritis: A prospective, randomized, open-label, active- and placebo-controlled trial

TUZUN, S; Uzun, Hafize; Aydin, S; DINC, A; SIPAHI, S; TOPCUOGLU, MA; YÜCEL, Rauf; Belce, Ahmet

doi:10.1016/j.curtheres.2005.08.002

Effects of flurbiprofen and tiaprofenic acid on oxidative stress markers in osteoarthritis: A prospective, randomized, open-label, active- and placebo-controlled trial

Atıf İçin Kopyala

TUZUN S., Uzun H., Aydin S., DINC A., SIPAHI S., TOPCUOGLU M., ...Daha Fazla

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, cilt.66, sa.4, ss.335-344, 2005 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 66 Sayı: 4
Basım Tarihi: 2005
Doi Numarası: 10.1016/j.curtheres.2005.08.002
Dergi Adı: CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.335-344
İstanbul Üniversitesi Adresli: Evet

Özet

Background: The relationship between oxidative stress and osteoarthritis (OA) has been widely investigated. Serum malondialdehyde (MDA), nitric oxide (NO), and Cu/Zn superoxide dismutase (SOD) levels are useful markers of oxidative stress. Because of the importance of oxidative stress markers in the pathogenesis of OA, treatment might involve modification of these markers to control oxidative stress.