Two bivalve's species (Chamelea gallina and Donax trunculus) were investigated in terms of proximate and mineral compositions (sodium, potassium, magnesium, calcium, iodine and selenium) throughout the year. The concentrations of minerals were determined using inductively coupled plasma mass spectrometry. Ranges of moisture, protein, fat, ash and carbohydrate contents were 82.70-86.57%, 6.86-8.99%, 0.58-1.20%, 2.44-2.95% and 2.70-4.50% for C. gallina, and were 81.09-85.55%, 8.13-10.61%, 0.69-1.33%, 3.19-4.06% and 2.31-3.18% for D. trunculus, respectively. The highest sodium, potassium, magnesium, calcium, iodine and selenium contents for two species were found in the summer, followed by spring, autumn and winter. The concentrations of metals in two tissues exceeded the acceptable levels for a food source for human consumption.