Comparison of the efficacy of once- and twice-daily colchicine dosage in pediatric patients with familial Mediterranean fever - a randomized controlled noninferiority trial

POLAT, Adem; Acikel, Cengizhan; Sozeri, Betul; DURSUN, İSMAİL; Kasapcopur, Özgür; GULEZ, Nesrin; SIMSEK, Dogan; SALDIR, Mehmet; Dokurel, Ipek; Poyrazoglu, Hakan; Bakkaloglu, Sevcan; Delibas, Ali; Ekinci, Zelal; AYAZ, Nuray; Kandur, Yasar; Peru, Harun; KURT, Yasemin; POLAT, Safiye; Unsal, Erbil; Makay, Balahan; GOK, Faysal; Ozen, Seza; Demirkaya, Erkan

doi:10.1186/s13075-016-0980-7

Comparison of the efficacy of once- and twice-daily colchicine dosage in pediatric patients with familial Mediterranean fever - a randomized controlled noninferiority trial

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POLAT A., Acikel C., Sozeri B., DURSUN İ., Kasapcopur O., GULEZ N., ...More

ARTHRITIS RESEARCH & THERAPY, vol.18, 2016 (SCI-Expanded)

Publication Type: Article / Article
Volume: 18
Publication Date: 2016
Doi Number: 10.1186/s13075-016-0980-7
Journal Name: ARTHRITIS RESEARCH & THERAPY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Keywords: Familial Mediterranean fever, Pediatric, Colchicine, Dosage schema, SUBCLINICAL INFLAMMATION, DISPOSITION, LEUKOCYTES, DIAGNOSIS, SEVERITY, CRITERIA, DISEASE
Istanbul University Affiliated: Yes

Abstract

Background: In this study, we examined the efficacy and safety of a once-daily dosage schema of colchicine compared with a twice-daily dosage schema in pediatric patients with familial Mediterranean fever (FMF).