Evaluation of Serum Paraoxonase and Arylesterase Activities in Subjects with Asthma and Chronic Obstructive Lung Disease


Acay A., Erdenen F., Altunoglu E., Erman H., Muderrisoglu C., Korkmaz G. G., ...Daha Fazla

CLINICAL LABORATORY, cilt.59, ss.1331-1337, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 59
  • Basım Tarihi: 2013
  • Doi Numarası: 10.7754/clin.lab.2013.121144
  • Dergi Adı: CLINICAL LABORATORY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1331-1337
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Asthma and chronic obstructive lung disease (COPD) are characterised by airway inflammation. Paraoxonase1 (PON1) and arylesterase (AE) enzymes have the ability to protect HDL from oxidation and may have antiatherogenic, antioxidant, and antiinflammatory features. We carried out a study to assess if there is a difference between PON1 and AE activities and biochemical values between asthmatics and COPD patients and if there is a difference between comorbid or pure COPD patients.