DIFFERENT EFFECTS OF CAV1 rs3807990 VARIATION ON LIPID PROFILE IN PATIENTS WITH CORONARY HEART DISEASE BASED ON PRESENCE OF DIABETES

Kurnaz-Gomleksiz, Ozlem; Ilikay, Serap; Bugra, Melike; Ozturk, Oğuz; Aydogan, Hulya

doi:10.26650/iuitfd.2018.0023

DIFFERENT EFFECTS OF CAV1 rs3807990 VARIATION ON LIPID PROFILE IN PATIENTS WITH CORONARY HEART DISEASE BASED ON PRESENCE OF DIABETES

Atıf İçin Kopyala

Kurnaz-Gomleksiz O., Ilikay S., Bugra Z., Ozturk O., Aydogan H. Y.

JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, cilt.83, sa.1, ss.23-29, 2020 (ESCI)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 83 Sayı: 1
Basım Tarihi: 2020
Doi Numarası: 10.26650/iuitfd.2018.0023
Dergi Adı: JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.23-29
İstanbul Üniversitesi Adresli: Evet

Özet

Objective: A decreased antiatherogenic function of endothelium causes endothelial dysfunction characterized by decreased nitric oxide (NO) levels. NO amounts can be regulated by the inhibition of eNOS enzyme activity via caveolin-1 (Cav-1). We aimed to determine the effect of CAV1 rs3807990 on metabolic and lipid biomarker levels in diabetic and non-diabetic coronary heart disease (CHD) and to determine the possible contribution to diabetic dyslipidemia.