Association between reduced levels of MEFV messenger RNA in peripheral blood leukocytes and acute inflammation


Ustek D. , EKMEKCI C. G. , Selcukbiricik F. , Cakiris A. , OKU B., Vural B. , ...Daha Fazla

ARTHRITIS AND RHEUMATISM, cilt.56, ss.345-350, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 56 Konu: 1
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1002/art.22320
  • Dergi Adı: ARTHRITIS AND RHEUMATISM
  • Sayfa Sayıları: ss.345-350

Özet

Objective. Familial Mediterranean fever (FMF) is associated with more than 70 missense mutations in the MEFV gene. The purpose of this study was to investigate the relative expression of messenger RNA (mRNA) for the MEFV gene in peripheral blood leukocytes (PBLs) obtained from patients with FMF during attacks of acute abdominal inflammation as well as during asymptomatic periods.