Fragmentation Analysis of Plasma DNA Reveals Its Prognostic Value in Gastric Cancer
TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.32, sa.9, ss.720-726, 2021 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 32 Sayı: 9
- Basım Tarihi: 2021
- Doi Numarası: 10.5152/tjg.2021.20832
- Dergi Adı: TURKISH JOURNAL OF GASTROENTEROLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.720-726
- Anahtar Kelimeler: Circulating nucleosome, DNA integrity, gastric cancer, plasma, CELL-FREE DNA, INTEGRITY, SERUM, NUCLEOSOMES, DIAGNOSIS, BENIGN, BLOOD, TOOL
- İstanbul Üniversitesi Adresli: Evet
Özet
Background: Gastric cancer (GC) is a common cause of cancer-related deaths. The poor clinical outcome in GC patients is partially associated with a lack of appropriate diagnostic and prognostic biomarkers. In the present study, we evaluated the diagnostic and prognostic values of cell-free DNA (cfDNA) integrity and the concentration of circulating nucleosomes (cNUCs).