VKORC1 and CYP2C9 polymorphisms are associated with warfarin dose requirements in Turkish patients

Ozgon, G.; Langaee, T.; feng, h; Buyru, Ayşe; Ulutin, T.; Hatemi, A.; Siva, A.; Saip, Sabahattin; Johnson, J.

doi:10.1007/s00228-008-0507-5

VKORC1 and CYP2C9 polymorphisms are associated with warfarin dose requirements in Turkish patients

Ozgon G. O., Langaee T. Y., feng h., Buyru N., Ulutin T., Hatemi A. C., ...More

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, vol.64, no.9, pp.889-894, 2008 (SCI-Expanded)

Publication Type: Article / Article
Volume: 64 Issue: 9
Publication Date: 2008
Doi Number: 10.1007/s00228-008-0507-5
Journal Name: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.889-894
Istanbul University Affiliated: Yes

Abstract

Objectives The objective of this study was to determine the quantitative influence of vitamin K epoxide reductase complex subunit 1 (VKORC1) and cytochrome P450 2C9 (CYP 2C9) polymorphisms on warfarin dose requirements in Turkish patients.