VKORC1 and CYP2C9 polymorphisms are associated with warfarin dose requirements in Turkish patients


Ozgon G. O. , Langaee T. Y. , feng h., Buyru N. , Ulutin T., Hatemi A. C. , ...More

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, vol.64, no.9, pp.889-894, 2008 (Journal Indexed in SCI) identifier identifier identifier

Abstract

Objectives The objective of this study was to determine the quantitative influence of vitamin K epoxide reductase complex subunit 1 (VKORC1) and cytochrome P450 2C9 (CYP 2C9) polymorphisms on warfarin dose requirements in Turkish patients.