Radiotherapy with or without mitomycin c in the treatment of locally advanced head and neck cancer: results of the IAEA multicentre randomised trial


Grau C., Agarwal J., Jabeen K., Khan A., Abeyakoon S., Hadjieva T., ...Daha Fazla

RADIOTHERAPY AND ONCOLOGY, cilt.67, ss.17-26, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 67 Konu: 1
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1016/s0167-8140(03)00020-3
  • Dergi Adı: RADIOTHERAPY AND ONCOLOGY
  • Sayfa Sayıları: ss.17-26

Özet

Background and purpose: Single agent mitomycin c (MMC) has been shown to improve the outcome of radiotherapy in single institution trials. In order to confirm these findings in a broader worldwide setting, the International Atomic Energy Agency (IAEA) initiated a multicentre trial randomising between radiotherapy alone versus radiotherapy plus MMC.