Effect of glutathione on brain nitric oxide levels in an experimental epilepsy mouse model

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AKÇALI A., PENÇE S., KURTUL N., BOŞNAK M., NEYAL M.

NEURAL REGENERATION RESEARCH, vol.4, no.9, pp.704-709, 2009 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 4 Issue: 9
• Publication Date: 2009
• Doi Number: 10.3969/j.issn.1673-5374.2009.09.012
• Journal Name: NEURAL REGENERATION RESEARCH
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.704-709
• Istanbul University Affiliated: No

Abstract

BACKGROUND: Oxidative stress plays an important role in the pathophysiology of epilepsy. Glutathione, known as one of the compounds of antioxidant defense, has been shown to inhibit convulsions. Nitric oxide has a proconvulsant effect on a pentylenetetrazole-induced animal model.