Spontaneous Pneumothorax in Children with Osteosarcoma: Report of Three Cases and Review of the Literature

Fayda M., Kebudi R., Dizdar Y., Gorgun O., Gun F., Aksu G., ...More

ACTA CHIRURGICA BELGICA, vol.112, no.5, pp.378-381, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 112 Issue: 5
  • Publication Date: 2012
  • Doi Number: 10.1080/00015458.2012.11680856
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.378-381
  • Istanbul University Affiliated: Yes


Spontaneous pneumothorax is a rare manifestation of primary lung cancer or metastasis. It is estimated that <1 % of all cases of spontaneous pneumothorax are tumor-associated and metastatic osteogenic or soft-tissue sarcomas are associated most commonly with pneumothorax especially in the setting of cytotoxic chemotherapy or radiotherapy. In this article, we report three pediatric cases with osteosarcoma that developed spontaneous pneumothorax during chemotherapy with a review of the literature. Two of them had lung metastasis at the time of the detection of pneumothorax and the remaining patient was found to have a bronchopleural fistula.