Anorectal manometry during the neonatal period: Its specificity in the diagnosis of Hirschsprung's disease


Emir H., Akman M., Sarimurat N., Kilic N., Erdogan E., Soylet Y.

EUROPEAN JOURNAL OF PEDIATRIC SURGERY, cilt.9, ss.101-103, 1999 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Konu: 2
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1055/s-2008-1072221
  • Dergi Adı: EUROPEAN JOURNAL OF PEDIATRIC SURGERY
  • Sayfa Sayıları: ss.101-103

Özet

In this study the reliability of anorectal manometry (ARMM) in Hirschsprung's disease (HD) in the neonatal period is evaluated. ARMM was performed in 59 patients (age ranging between 2 to 90 days) in whom HD was suspected. Rectal biopsy was performed in 23 newborn whose rectoanal inhibitory reflex (RAIR) was not identified in the ARMM study and in 13 RAIR-positive newborn due to strong clinical signs supporting HD or persistence of symptoms during their follow-up. Other RAIR-positive patients were followed up to 4 months to 3.5 years and no problems were encountered. Among the 36 newborn with rectal biopsies, if the results were compared to ARMM studies, there were one false-positive and two false-negative results. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of ARMM in the diagnosis of HD are 91.6 %, 95.6 %, 84.6 % and 91.6 % respectively. We conclude that ARMM can be used as a screening test in patients in whom HD is suspected during the neonatal period, but for definitive diagnosis it must be combined with other diagnostic tests.