A solitary calvarial lytic lesion with typical histopathological findings of juvenile hyaline fibromatosis - Case report

Bas N., Guzey F., Emel E., Cefle K., Turgut H., Alatas I., ...Daha Fazla

JOURNAL OF NEUROSURGERY, cilt.103, sa.3, ss.285-288, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 103 Konu: 3
  • Basım Tarihi: 2005
  • Sayfa Sayıları: ss.285-288


Juvenile hyaline fibromatosis (JHF) is a rare systemic disease characterized by papulonodular skin lesions, gingivalhyperplasia, joint contractures, and osteolytic lesions on long bones and the skull. It has recently been reported that the disease is caused by mutations in the gene encoding capillary morphogenesis protein-2 (CMG-2). To date, fewer than 60 cases have been published in the literature. Partial disease expression is common, but no cases featuring a solitary calvarial lesion have been reported.