A solitary calvarial lytic lesion with typical histopathological findings of juvenile hyaline fibromatosis - Case report
JOURNAL OF NEUROSURGERY, vol.103, no.3, pp.285-288, 2005 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 103 Issue: 3
- Publication Date: 2005
- Journal Name: JOURNAL OF NEUROSURGERY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.285-288
- Istanbul University Affiliated: Yes
Abstract
Juvenile hyaline fibromatosis (JHF) is a rare systemic disease characterized by papulonodular skin lesions, gingivalhyperplasia, joint contractures, and osteolytic lesions on long bones and the skull. It has recently been reported that the disease is caused by mutations in the gene encoding capillary morphogenesis protein-2 (CMG-2). To date, fewer than 60 cases have been published in the literature. Partial disease expression is common, but no cases featuring a solitary calvarial lesion have been reported.